AUTHORS : Alepee N. Bouez C Cotovio J Dakic V De Vecchi R Garcia C Mattos G Oliveira V Rigaudeau A-S MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : PERCUTANEOUS ABSORPTION Permeability PHARMACOLOGY / TOXICOLOGY Skin corrosion Skin irritation SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS SKIN METABOLISM Implementation, availability and regulatory status of an OECD accepted Reconstructed Human Epidermis model in Brazil 2018 Vigil. sanit. debate 2018;6(1):64-71 | L'Oréal, EPISKIN
AUTHORS : Alepee N. Cotovio J Grandidier MH Tornier C MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : Skin corrosion SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS An integrated testing strategy for in vitro skin corrosion and irritation assessment using SkinEthic™ Reconstructed Human Epidermis. 2015 Toxicology in Vitro 29 (2015) 1779–1792 | L'Oréal, Episkin
AUTHORS : Alepee N. Cotovio J Grandidier MH MODELS : EPISKIN APPLICATIONS : Skin corrosion SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS In vitro skin corrosion and irritation assessment of ingredients using EpiSkin methods: Sequential Top-Down and Bottom-Up approaches 2014 L'Oreal (WC9) | L’Oréal Research & Innovation, France
AUTHORS : Alepee N. Cotovio J Grandidier MH MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : Skin corrosion SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS Integrated approach for skin corrosion and skin irritation using in vitro SkinEthic RHE test methods 2014 | L'Oréal
AUTHORS : Alves RC Beatriz M Ferreira M Helena Amaral M Oliveira PP Pereira C Pimentel FB Rodrigues F Sarmento B MODELS : EPISKIN HCE / HUMAN CORNEAL EPITHELIUM APPLICATIONS : SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS Are coffee silverskin extracts safe for topical use? An in vitro andin vivo approachF 2014 Elsevier | REQUIMTE, INEB, Inovapotek, IINFACTS, Department of Drug Sciences, Laboratory of Pharmaceutical Technology, Fourmag Lda
AUTHORS : Antignac E. Clouzeau J. Persaud R. Re Thomas Srinivasan V. MODELS : EPISKIN HCE / HUMAN CORNEAL EPITHELIUM RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : GENOTOXICITY OCULAR IRRITATION OF CHEMICAL PHARMACOLOGY / TOXICOLOGY PHOTOPROTECTION Phototoxicity SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS SKIN SENSITIZATION SYSTEMIC TOXICITY Safety Assessment of Botanicals: A Decision Tree Approach for the Safety Assessment of Botanical Cosmetic Ingredients 2012 SOT Society of Toxicology annual meeting | L'Oréal, Research & Innovation
AUTHORS : Auriault C. Cotovio J Cottrez F. Groux H. Lelièvre D Meunier Jean-Roch MODELS : EPISKIN APPLICATIONS : SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS IRR-IS® - EpiSkinTM based model for Irritation - Evaluation of IRR-IS®, an EpiSkinTM based model for Quantifying Chemical Irritation Potency 2012 SOT Society of Toxicology annual meeting | L’Oréal Research and Innovation, ImmunoSearch
AUTHORS : Alepee N. Amsellem Carole de Brugerolle de Fraissinette A Doucet O Meloni M Pachot Jean Robert C Roux Marie-Helene Tornier C MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS A catch-up validation study on reconstructed human epidermis (SkinEthicTM RHE) 2010 Toxicology in vitro | SkinEthic, L'Oréal, Episkin, Oroxcell, Vitroscreen, Coty
AUTHORS : Alepee N. Amsellem Carole de Brugerolle de Fraissinette A. Doucet O Meloni M Pachot Jean Robert C Roux Marie-Helene Tornier C MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS A catch-up validation study on reconstructed human epidermis (SkinEthic RHE) for full replacement of the Draize skin irritation test. 2010 Toxicology In Vitro. 2010 Feb;24(1):257-66 | L'Oréal, Research & Innovation
AUTHORS : Alepee N. Amsellem Carole de Brugerolle de Fraissinette A. Tornier C MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS Assessment of the optimized SkinEthic Reconstructed Human Epidermis (RHE) 42 bis skin irritation protocol over 39 test substances. 2010 Toxicology In Vitro. 2010 Feb;24(1):245-56 | SkinEthic