AUTHORS : Alepee N. Bouez C Cotovio J Dakic V De Vecchi R Garcia C Mattos G Oliveira V Rigaudeau A-S MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : PERCUTANEOUS ABSORPTION Permeability PHARMACOLOGY / TOXICOLOGY Skin corrosion Skin irritation SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS SKIN METABOLISM Implementation, availability and regulatory status of an OECD accepted Reconstructed Human Epidermis model in Brazil 2018 Vigil. sanit. debate 2018;6(1):64-71 | L'Oréal, EPISKIN
AUTHORS : Aleksic Maja Kitteringham Neil R Naisbitt Dean J Olayanju Adedamola Sheffield David Spriggs Sandrine MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : SKIN METABOLISM SKIN SENSITIZATION Effect of Repeated Daily Dosing with 2,4-Dinitrochlorobenzene on Glutathione Biosynthesis and Nrf2 Activation in Reconstructed Human Epidermis 2016 SOT Society of Toxicology | Unilever
AUTHORS : Budimir N. Duché Daniel Eilstein Joan Hussler G. Lereaux Guillaume Wilkinson S. MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : SKIN METABOLISM Comparison of xenobiotic metabolizing enzyme activities in ex vivo human skin and reconstructed human skin models from SkinEthic. 2014 Archives of Toxicology. 2014, March 22 | L'Oréal, Research & Innovation
AUTHORS : Duché Daniel Eilstein Joan Garrigues A. Lereaux Guillaume Meunier Jean-Roch MODELS : EPISKIN RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : SKIN METABOLISM Characterization of peroxidase activities in normal human skin compared with reconstructed human skin models 2013 Society of Toxicology (SOT) Annual meeting |
AUTHORS : Alepee N. Cotovio J Duché Daniel Leclaire J Marrot L Ouedraogo G. Ovigne Jean-Marc Teissier M H MODELS : EPISKIN HCE / HUMAN CORNEAL EPITHELIUM RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : GENOTOXICITY OCULAR IRRITATION OF CHEMICAL Phototoxicity Skin corrosion SKIN IRRITATION OF CHEMICALS SKIN METABOLISM L’Oréal commitment in the develo pment, evaluation and validation of screening and testing approaches contributing to the 3Rs 2011 | L'Oréal
AUTHORS : Duché Daniel Eilstein Joan Leclaire J Lereaux Guillaume Meunier Jean-Roch APPLICATIONS : SKIN METABOLISM Cutaneous Metabolism 2011 | L'Oreal
AUTHORS : Duché Daniel Ferraris C Labrie Fernand Leclaire J Luu-The Van Meunier Jean-Roch MODELS : EPISKIN APPLICATIONS : SKIN METABOLISM Expression profiles of phases 1 and 2 metabolizing enzymes in human skin and the reconstructed skin models EpiskinTM and full thickness model from EpiskinTM 2009 Elsevier Journal of Steroid Biochemistry and Molecular Biology | L'Oréal, Episkin, SkinEthic
AUTHORS : Duché Daniel Ferraris C Labrie Fernand Leclaire J Luu-The Van Meunier Jean-Roch MODELS : EPISKIN APPLICATIONS : SKIN METABOLISM Expression profiles of phases 1 and 2 metabolizing enzymes in human skin and the reconstructed skin models Episkin and full thickness model from Episkin. 2009 J Steroid Biochem Mol Biol. 2009 Sep;116(3-5):178-86 | L'Oréal, Research & Innovation
AUTHORS : Cotovio J Leclaire J Roguet R MODELS : EPISKIN APPLICATIONS : PHARMACOLOGY / TOXICOLOGY SKIN METABOLISM Reconstructed skin for in vitro cutaneous pharmacotoxicology: Example of metabolic studies 1997 IN VITRO TOXICOL J MOL CELL TOXICOL. In Vitro Toxicology: Journal of Molecular and Cellular Toxicology 1997 ;10 (1):3-9 | R. Roguet, Life Sciences, L'Oreal Advanced Res. Laboratories, 1 Avenue E. Schueller, 93600 Aulnay sous Bois
AUTHORS : Cotovio J Kremers P Leclaire J Pouradier Duteil X Roguet R Rougier A MODELS : EPISKIN APPLICATIONS : SKIN METABOLISM Cytochrome P450-dependent enzyme activities and testosterone metabolism in a reconstituted human epidermis 1995 In Vitro Toxicology: Journal of Molecular and Cellular Toxicology 1995 ;8 (1):97-104 | L'Oreal, Dept Central Securite Produits, 1, Avenue Eugene Schueller,93600 Aulnay sous Bois
AUTHORS : Berthod F. Collombel C Damour O Shahabeddin L APPLICATIONS : PHARMACOLOGY / TOXICOLOGY SKIN METABOLISM Characterization of skin reconstructed on a chitosan-cross-linked collagen-glycosaminoglycan matrix 1990 Skin Pharmacology 1990 ;3 (2):107-114 | Laboratoire de Substituts Cutanes (CNRS-URA 1341), Hopital Edouard Herriot, Pavillon 15, Place Arsonval, F-69437 Lyon
AUTHORS : Bernard B. A. Jamoulle J C Lenoir M C Magdalou J Pham M A Shroot B Siest G APPLICATIONS : PHARMACOLOGY / TOXICOLOGY SKIN METABOLISM Reconstituted epidermis: a novel model for the study of drug metabolism in human epidermis 1990 J Invest Dermatol 1990 ;94 (6):749-52 | Centre du Medicament Nancy, France.
AUTHORS : Dubertret L APPLICATIONS : PHARMACOLOGY / TOXICOLOGY SKIN METABOLISM Reconstruction of the human skin equivalent in vitro: a new tool for skin biology 1990 Skin Pharmacol 1990 ;3 (2):144-8 | Laboratoire de Dermatologie, INSERM U, Hopital St. Louis, Paris, France.