AUTHORS : Alepee N. Bouez C Cotovio J Dakic V De Vecchi R Garcia C Mattos G Oliveira V Rigaudeau A-S MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : PERCUTANEOUS ABSORPTION Permeability PHARMACOLOGY / TOXICOLOGY Skin corrosion Skin irritation SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS SKIN METABOLISM Implementation, availability and regulatory status of an OECD accepted Reconstructed Human Epidermis model in Brazil 2018 Vigil. sanit. debate 2018;6(1):64-71 | L'Oréal, EPISKIN
AUTHORS : Alepee N. Cotovio J Grandidier MH Tornier C MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : Skin corrosion SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS An integrated testing strategy for in vitro skin corrosion and irritation assessment using SkinEthic™ Reconstructed Human Epidermis. 2015 Toxicology in Vitro 29 (2015) 1779–1792 | L'Oréal, Episkin
AUTHORS : Alepee N. Cotovio J Grandidier MH MODELS : EPISKIN APPLICATIONS : Skin corrosion SKIN IRRITATION OF CHEMICALS In vitro skin Corrosion and Irritation Assessment of Ingredients Using Episkin Model: Top-Down and Bottom-Up Approaches 2014 Society of Toxicology (SOT) Annual Meeting | L'Oréal, Research & Innovation
AUTHORS : Alepee N. Cotovio J Grandidier MH MODELS : EPISKIN APPLICATIONS : Skin corrosion SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS In vitro skin corrosion and irritation assessment of ingredients using EpiSkin methods: Sequential Top-Down and Bottom-Up approaches 2014 L'Oreal (WC9) | L’Oréal Research & Innovation, France
AUTHORS : Alepee N. Cotovio J Grandidier MH MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : Skin corrosion SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS Integrated approach for skin corrosion and skin irritation using in vitro SkinEthic RHE test methods 2014 | L'Oréal
AUTHORS : Akbarsha MA Alonso Alain Pellevoisin C Riyasdeen A MODELS : EPISKIN RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : Skin corrosion SKIN IRRITATION OF CHEMICALS An Indian educational initiative to promote the use of alternatives to animal testing 2014 | Mahatma Gandhi-Doerenkamp Center for Alternatives to Use of Animals in Life Science Education, Episki, Episkin Academy, SkinEthic Academy
AUTHORS : Alves RC Beatriz M Ferreira M Helena Amaral M Oliveira PP Pereira C Pimentel FB Rodrigues F Sarmento B MODELS : EPISKIN HCE / HUMAN CORNEAL EPITHELIUM APPLICATIONS : SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS Are coffee silverskin extracts safe for topical use? An in vitro andin vivo approachF 2014 Elsevier | REQUIMTE, INEB, Inovapotek, IINFACTS, Department of Drug Sciences, Laboratory of Pharmaceutical Technology, Fourmag Lda
AUTHORS : Alepee N. Cotovio J Grandidier MH Gregoire S. Micheau Beatrice MODELS : EPISKIN APPLICATIONS : SKIN IRRITATION OF CHEMICALS Influence of acidic extraction conditions on formazan assay: Assessment of test substances using in vitro EpiSkin skin irritation test method by HPLC and colorimetry 2013 Society of Toxicology (SOT) Annual Meeting | L'Oréal, Research & Innovation
AUTHORS : Alepee N. Cotovio J Grandidier MH Leblanc V. Robert C Seyler N. Tornier C MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : Skin corrosion SKIN IRRITATION OF CHEMICALS The In vitro SkinEthic RHE Skin Corrosion as a Reference Test Method in the Acute Testing Strategy 2013 Society of Toxicology (SOT) Annual Meeting | L'Oréal, Research & Innovation
AUTHORS : Antignac E. Clouzeau J. Persaud R. Re Thomas Srinivasan V. MODELS : EPISKIN HCE / HUMAN CORNEAL EPITHELIUM RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : GENOTOXICITY OCULAR IRRITATION OF CHEMICAL PHARMACOLOGY / TOXICOLOGY PHOTOPROTECTION Phototoxicity SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS SKIN SENSITIZATION SYSTEMIC TOXICITY Safety Assessment of Botanicals: A Decision Tree Approach for the Safety Assessment of Botanical Cosmetic Ingredients 2012 SOT Society of Toxicology annual meeting | L'Oréal, Research & Innovation
AUTHORS : Alepee N. Cotovio J Grandidier MH Meunier Jean-Roch Seyler N. Soler Francoise MODELS : EPISKIN APPLICATIONS : Skin corrosion SKIN IRRITATION OF CHEMICALS SYSTEMIC TOXICITY EpiSkin Acute Dermal Toxicity Testing Strategy - OECD TG 404 Acute Dermal Toxicity Testing Strategy Combining the Use of the EpiSkin Validated Test Methods 2012 SOT Society of Toxicology annual meeting | L'Oréal, Research & Innovation
AUTHORS : Auriault C. Cotovio J Cottrez F. Groux H. Lelièvre D Meunier Jean-Roch MODELS : EPISKIN APPLICATIONS : SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS IRR-IS® - EpiSkinTM based model for Irritation - Evaluation of IRR-IS®, an EpiSkinTM based model for Quantifying Chemical Irritation Potency 2012 SOT Society of Toxicology annual meeting | L’Oréal Research and Innovation, ImmunoSearch
AUTHORS : de Brugerolle de Fraissinette A. Rosdy M Tornier C MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : SKIN IRRITATION OF CHEMICALS In vitro patc h test using non-invasive endpoints 2011 | SkinEthic
AUTHORS : Alepee N. Cotovio J Duché Daniel Leclaire J Marrot L Ouedraogo G. Ovigne Jean-Marc Teissier M H MODELS : EPISKIN HCE / HUMAN CORNEAL EPITHELIUM RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : GENOTOXICITY OCULAR IRRITATION OF CHEMICAL Phototoxicity Skin corrosion SKIN IRRITATION OF CHEMICALS SKIN METABOLISM L’Oréal commitment in the develo pment, evaluation and validation of screening and testing approaches contributing to the 3Rs 2011 | L'Oréal
AUTHORS : Alepee N. Cotovio J de Brugerolle de Fraissinette A. Grandidier M H Meunier Jean-Roch Roquet Manon Seyler N. Soler Francoise Tornier C MODELS : EPISKIN RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : SKIN IRRITATION OF CHEMICALS An Evaluation of the EpiSkinTM and SkinEthicTM RHE test methods for predicting dermal toxicity using OECD TG404 2011 | L'Oreal
AUTHORS : Alepee N. Cotovio J Grandidier MH Lelièvre D Meunier Jean-Roch Tornier C MODELS : EPISKIN RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : SKIN IRRITATION OF CHEMICALS Evaluation of the in vitro EpiSkin and SkinEthic RHE Skin Irritation test methods for hazard identification of chemicals 2011 |
AUTHORS : Detroyer A. Meunier Jean-Roch Note R. Prunier B. Rathman J.F. RINGEISEN Stephanie Schwab C.H. Yang C. MODELS : EPISKIN RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : SKIN IRRITATION OF CHEMICALS A mechanistic rationale for the prediction of skin irritancy effects implemented in a workflow process 2011 | L'Oreal
AUTHORS : Alepee N. Amsellem Carole de Brugerolle de Fraissinette A Doucet O Meloni M Pachot Jean Robert C Roux Marie-Helene Tornier C MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS A catch-up validation study on reconstructed human epidermis (SkinEthicTM RHE) 2010 Toxicology in vitro | SkinEthic, L'Oréal, Episkin, Oroxcell, Vitroscreen, Coty
AUTHORS : Blackstock C. Roper C. MODELS : EPISKIN APPLICATIONS : SKIN IRRITATION OF CHEMICALS Assessment of the Effects of Pre-Incubation Time on Irritation Potential Using the EpiSkin® in vitro Irritation Test 2010 | Charles River
AUTHORS : Alepee N. Amsellem Carole de Brugerolle de Fraissinette A. Doucet O Meloni M Pachot Jean Robert C Roux Marie-Helene Tornier C MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS A catch-up validation study on reconstructed human epidermis (SkinEthic RHE) for full replacement of the Draize skin irritation test. 2010 Toxicology In Vitro. 2010 Feb;24(1):257-66 | L'Oréal, Research & Innovation