Assessment of the optimized SkinEthic Reconstructed Human Epidermis (RHE) 42 bis skin irritation protocol over 39 test substances.
2010
Toxicology In Vitro. 2010 Feb;24(1):245-56 | SkinEthic
A catch-up validation study on reconstructed human epidermis (SkinEthicTM RHE) for full replacement of the Draize skin irritation test
2009
| SkinEthic
Assessment of the optimized SkinEthicTM Reconstructed Human Epidermis (RHE)
2009
| SkinEthic
The ECVAM international validation study on in vitro tests for acute skin irritation: report on the validity of the EPISKIN and EpiDerm assays and on the Skin Integrity Function Test.
2007
| Episkin
The ECVAM International Validation Study on In VitroTests for Acute Skin Irritation: Selection of Test Chemicals
2007
| Episkin
Assessment of the skin irritation potential of chemicals by using the SkinEthic reconstructed human epidermal model and the common skin irritation protocol evaluated in the ECVAM skin irritation validation study
2006
Altern Lab Anim. 2006 Aug;34(4):393-406 | ZEBET, National Centre for the Documentation and Evaluation of Alternative Methods to Animal Experiments, Federal Institute for Risk assessment (BfR), Diedersdorfer Weg 1, D-12277 Berlin, Germany. [email protected]
In vitro skin irritation testing on reconstituted human epidermis: reproducibility for 50 chemicals tested with two protocols
2006
Toxicol In Vitro. 2006 Jun;20(4):401-16. Epub 2005 Oct 17. | SkinEthic Laboratories, 45, rue Saint Philippe, 06000 Nice, France.
Optimisation of the EpiDerm test protocol for the upcoming ECVAM validation study on in vitro skin irritation tests
2004
ALTEX 2004 ;21 (3):107-14 | Centre for Documentation and Evaluation of Alternative Methods to Animal Experiments (ZEBET) at the BfR (Federal Institute for Risk Assessment), D-Berlin.
Using skin models to assess the effects of a protection cream on skin barrier function
2004
Skin Pharmacol Physiol 2004 ;17 (4):167-75 | Degussa, Stoko Skin Care, Laboratory for Toxicology and Ecology, Krefeld, Germany. [email protected]
The validation of in vitro methods for skin irritation
2004
Toxicol Lett 2004 ;149 (1-3):387-90 | Syngenta Central Toxicology Laboratory, Alderley Park, Macclesfield SK10 4TJ, UK. [email protected]
In vitro skin irritation: facts and future. State of the art review of mechanisms and models
2004
Toxicol In Vitro 2004 Jun ;18 (3):231-43 | VTB-Skin Biochemistry, Henkel KGaA, Building Z33, Henkelstrasse 67, D-40191, Duesseldorf, Germany. [email protected]
In vitro skin irritation: facts and future. State of the art review of mechanisms and models.
2004
Toxicol In Vitro. 2004 Jun;18(3):231-43. | VTB-Skin Biochemistry, Henkel KGaA, Building Z33, Henkelstrasse 67, D-40191, Duesseldorf, Germany. [email protected]
Alternative methods for evaluating skin irritation using three-dimensional cultures
2003
EXOGENOUS DERMATOL. Exogenous Dermatology 2003 ;2 (1):1-5 | Dr. H.C. Eun, Department of Dermatology, Seoul Natl. Univ. Coll. of Medicine, 28 Yongon-dong, Chongno-gu Seoul 110-744 EML: [email protected]
Analysis of interleukin-1alpha (IL-1alpha) and interleukin-8 (IL-8) expression and release in in vitro reconstructed human epidermis for the prediction of in vivo skin irritation and/or sensitization
2003
Toxicol In Vitro 2003 ;17 (3):311-21 | Department of Biology, SGS Biopharma S.A., Vieux Chemin du Poete 10, B-1301, Wavre, Belgium. [email protected]
Induction of adipose differentiation related protein and neutral lipid droplet accumulation in keratinocytes by skin irritants
2003
J Invest Dermatol 2003 ;121 (2):337-44 | Laboratory of Toxicology, Department of Pharmacological Sciences, University of Milan, Italy. [email protected]
A prevalidation study on the in vitro skin irritation function test (SIFT) for prediction of acute skin irritation in vivo: results and evaluation of ECVAM Phase III
2003
Toxicol In Vitro 2003 ;17 (2):123-38 |
Alternatives to animal testing: research, trends, validation, regulatory acceptance
2003
ALTEX 2003 ;20 (Suppl 1):3-61 | Toxicology Consulting Services, Plainsboro, USA.
In vitro evaluation of skin sensitivity of povidone-iodine and other antiseptics using a three-dimensional human skin model
2002
Dermatology 2002 ;204 Suppl 1):109-13 | Pharmaceutical Research Center, Meiji Seika Kaisha, Yokohama, Japan. [email protected]
Non-animal testing strategies for assessment of the skin corrosion and skin irritation potential of ingredients and finished products
2002
Food Chem Toxicol 2002 ;40 (5):573-92 | Human & Environmental Safety Division, The Procter & Gamble Co., Miami Valley Laboratories, Cincinnati, OH, USA. [email protected]
Predictive ability of reconstructed human epidermis equivalents for the assessment of skin irritation of cosmetics
2002
Toxicol In Vitro 2002 ;16 (5):557-72 | Cosmital SA (Research Company of Wella AG, Germany), Rte de Chesalles 21, CH-1723 Marly, Switzerland. [email protected]