Reconstructed skin kits: reproducibility of cutaneous irritancy testing
2002
Skin Pharmacol Appl Skin Physiol 2002 ;15 Suppl 1):74-91 | Cosmital SA (Research Company of Wella AG, Germany), Marly, Switzerland. [email protected]
Utility of MTT assay in three-dimensional cultured human skin model as an alternative for draize skin irritation test: approach using diffusion law of irritant in skin and toxicokinetics-toxicodynamics correlation
2002
Pharm Res 2002 ;19 (5):669-75 | Faculty of Pharmaceutical Sciences, Josai University, Sakado, Saitama, Japan.
ECVAM, ECETOC and the EU Chemicals Policy. Alternatives to animal experiments: Progress made and challenges ahead. The proceedings of the ECVAM Status Seminar 2002, held on 4-6 June 2002, in the amphitheatre at the European Commission Joint Research Centr
2002
ATLA Alternatives to laboratory animals 2002 ;30 (SUP2):185-187 | Syngenta Central Toxicology Laboratory, Alderley Park, Macclesfield, Cheshire, SK10 4TJ, United Kingdom
Follow-up to the ECVAM prevalidation study on in vitro tests for acute skin irritation. The European Centre for the Validation of Alternative Methods Skin Irritation Task Force report 2
2002
(2002) ATLA 30, 109-129 | ECVAM, Institute for Health & Consumer Protection, European Commission Joint Research Centre, 21020 Ispra (VA), Italy
Currently available in vitro methods used in the regulatory toxicology
2002
Toxicol Lett 2002 Feb 28 ;127 (1-3):127-34 | National Centre for Documentation and Evaluation of Alternative Methods to Animal Experiments (ZEBET), Federal Institute for Health Protection of Consumers and Veterinary Medicine (BgVV), Diedersdorfer Weg 1, D-12277 Berlin, Germany. [email protected]
The use and interpretation of in vitro data in regulatory toxicology: cosmetics, toiletries and household products
2002
Toxicol Lett 2002 Feb 28 ;127 (1-3):177-82 | Health and Safety Executive, Magdalen House, Stanley Precinct, Bootle, Merseyside L20 3QZ, UK. [email protected]
Refinement of the Episkin protocol for the assessment of acute skin irritation of chemicals: follow-up to the ECVAM prevalidation study
2002
Toxicol In Vitro 2002 Dec ;16 (6):765-70 | L'Oreal Recherche, Aulnay sous Bois, France. [email protected]
Induction of HSP27 nuclear immunoreactivity during stress is modulated by vitamin C
2002
Exp Dermatol 2002 Dec ;11 (6):509-17 | Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.
ECVAM's activities in validating alternative tests for skin corrosion and irritation
2002
Altern Lab Anim 2002 Dec ;30 Suppl 2):61-7 | Safety & Environmental Assurance Centre (SEAC), Unilever Colworth Laboratory, Sharnbrook, Bedfordshire MK44 1LQ, UK.
Comparison of tissue sources for the skin integrity function test (SIFT)
2001
Toxicol In Vitro 2001 ;15 (4-5):597-600 | Absorption and In Vitro Toxicology Unit, Syngenta Central Toxicology Laboratory, Alderley Park, Macclesfield, Cheshire SK10 4TJ, UK. [email protected]
Gene expression analysis of EpiDerm following exposure to SLS using cDNA microarrays
2001
Toxicol In Vitro 2001 ;15 (4-5):393-8 |
A prevalidation study on in vitro tests for acute skin irritation. results and evaluation by the Management Team
2001
Toxicol In Vitro 2001 Feb ;15 (1):57-93 | Unilever Research, Colworth House, Sharnbrook, Bedfordshire MK44 1LQ, UK. [email protected]
In vitro and human testing strategies for skin irritation
2000
Ann N Y Acad Sci 2000 ;919):192-204 |
Use of human skin equivalent Apligraf for in vitro assessment of cumulative skin irritation potential of topical products
2000
Toxicol Appl Pharmacol 2000 ;164 (1):38-45 | Preclinical Safety Department, Novartis Pharma AG, Basel, CH-4002, Switzerland. [email protected]
Local irritation/corrosion testing strategies : Development of a decision support system for the introduction of alternative methods
2000
ATLA Alternatives to laboratory animals 2000 ;28 (1):29-40 | Federal Institute for Health Protection of Consumers and Veterinary Medicine (BgVV), Thielallee 88-92, 14195 Berlin, Germany
Characterization and comparison of reconstructed skin models: morphological and immunohistochemical evaluation
2000
Acta Derm Venereol. 2000 Mar-Apr;80(2):82-8. | Department of Dermatology, Leiden University Medical Center, The Netherlands
Differential expression and release of cytokines by an in vitro reconstructed human epidermis following exposure to skin irritant and sensitizing chemicals
1999
Toxicology in Vitro 1999 ;13 (6):867-877 | A. Coquette, SGS Biopharma S.A., Vieux Chemin du Poete 10, B-1301 Wavre
Use of skin cell cultures for in vitro assessment of corrosion and cutaneous irritancy
1999
Cell Biol Toxicol 1999 ;15 (1):63-75 | Life Sciences Research, L'Oreal Recherche, Clichy, France.
Use of skin cell cultures for in vitro assessment of corrosion and cutaneous irritancy
1999
Cell Biol Toxicol 1999 Feb ;15(1):63-75 | Life Sciences Research, L'Oreal Recherche, Clichy, France
Potential cosmetic applications of reconstructed epidermis
1999
Toxicology in vitro 1999 ;21 (1):51-58 | L'Oreal, Centre Charles ZVIAK, Life Science Research, 90 rue du General Roguet, 92583 Clichy, France