AUTHORS : Alepee N. Bouez C Cotovio J Dakic V De Vecchi R Garcia C Mattos G Oliveira V Rigaudeau A-S MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : PERCUTANEOUS ABSORPTION Permeability PHARMACOLOGY / TOXICOLOGY Skin corrosion Skin irritation SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS SKIN METABOLISM Implementation, availability and regulatory status of an OECD accepted Reconstructed Human Epidermis model in Brazil 2018 Vigil. sanit. debate 2018;6(1):64-71 | L'Oréal, EPISKIN
AUTHORS : Alepee N. Cotovio J Grandidier MH Tornier C MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : Skin corrosion SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS An integrated testing strategy for in vitro skin corrosion and irritation assessment using SkinEthic™ Reconstructed Human Epidermis. 2015 Toxicology in Vitro 29 (2015) 1779–1792 | L'Oréal, Episkin
AUTHORS : Alepee N. Cotovio J Grandidier MH MODELS : EPISKIN APPLICATIONS : Skin corrosion SKIN IRRITATION OF CHEMICALS In vitro skin Corrosion and Irritation Assessment of Ingredients Using Episkin Model: Top-Down and Bottom-Up Approaches 2014 Society of Toxicology (SOT) Annual Meeting | L'Oréal, Research & Innovation
AUTHORS : Alepee N. Cotovio J Robert C Tornier C MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : Skin corrosion The usefulness of the validated SkinEthic™ RHE test method to identify skin corrosive UN GHS subcategories. 2014 Toxicology In Vitro, 2014, June; 28(4)-616-25 | SkinEthic, L'Oréal, Research & Innovation
AUTHORS : Alepee N. Cotovio J Grandidier MH MODELS : EPISKIN APPLICATIONS : Skin corrosion Sub-categorisation of skin corrosive chemicals by the EpiSkin™ reconstructed human epidermis skin corrosion test method according to UN GHS: revision of OECD Test Guideline 431. 2014 Toxicology In Vitro. 2014 Mar;28(2):131-45 | L'Oréal, Research & Innovation
AUTHORS : Alepee N. Cotovio J Grandidier MH MODELS : EPISKIN APPLICATIONS : Skin corrosion SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS In vitro skin corrosion and irritation assessment of ingredients using EpiSkin methods: Sequential Top-Down and Bottom-Up approaches 2014 L'Oreal (WC9) | L’Oréal Research & Innovation, France
AUTHORS : Alepee N. Cotovio J Tornier C MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : Skin corrosion SkinEthic RHE method categorises chemicals between corrosive subcategories and non-corrosive as stated in OECD TG431 2014 | Episkin, L'Oréal
AUTHORS : Alepee N. Cotovio J Grandidier MH MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : Skin corrosion SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS Integrated approach for skin corrosion and skin irritation using in vitro SkinEthic RHE test methods 2014 | L'Oréal
AUTHORS : Cotovio J Cottrez F. Del Bufalo Aurelia Groux H. Martinozzi-Teissier S. Tourneix F. MODELS : EPISKIN APPLICATIONS : SKIN SENSITIZATION Evaluation of SENS-IS®, an Episkin® based model for identifying chemical sensitizers of fragrance ingredients 2014 | L'Oréal, Immunosearch
AUTHORS : Alepee N. Cotovio J Grandidier M H MODELS : EPISKIN APPLICATIONS : Skin corrosion IN VITRO EPISKINTM SKIN CORROSION AS A REFERENCE TEST METHOD IN OECD TG431 FOR THE ASSESSMENT OF SKIN CORROSION IN SUB-CATEGORIES 1A, 1B AND 1C 2013 Society of Toxicology | L'Oreal
AUTHORS : Alepee N. Bessou S. Cotovio J De Smedt A De Wever B Faller C Jones P A Le Varlet Béatrice Marrec-Fairley M McNamee P Pfannenbecker U Tailhardat M Van Goethem F MODELS : HCE / HUMAN CORNEAL EPITHELIUM APPLICATIONS : OCULAR IRRITATION OF CHEMICAL Cosmetics Europe Multi-Laboratory Pre-Validation of the SkinEthic™ Reconstituted Human Corneal Epithelium Test Method for the Prediction of Eye Irritation. 2013 Toxicology in vitro | L'Oreal
AUTHORS : Alepee N. Cotovio J Grandidier MH Gregoire S. Micheau Beatrice MODELS : EPISKIN APPLICATIONS : SKIN IRRITATION OF CHEMICALS Influence of acidic extraction conditions on formazan assay: Assessment of test substances using in vitro EpiSkin skin irritation test method by HPLC and colorimetry 2013 Society of Toxicology (SOT) Annual Meeting | L'Oréal, Research & Innovation
AUTHORS : Alepee N. Cotovio J Grandidier MH MODELS : EPISKIN APPLICATIONS : Skin corrosion In vitro EpiSkin skin corrosion as a reference test method in OECD TG431 for the assessment of skin corrosion in sub-categories 1A, 1B and 1C 2013 Society of Toxicology (SOT) Annual Meeting | L'Oréal, Research & Innovation
AUTHORS : Alepee N. Cotovio J Tornier C MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : Skin corrosion The Usefulness of the Validated SkinEthic RHE Method to Identify Skin Corrosive UN GHS Subcategories 2013 Society of Toxicology (SOT) Annual Meeting | L'Oréal, Research & Innovation
AUTHORS : Alepee N. Cotovio J Grandidier MH Leblanc V. Robert C Seyler N. Tornier C MODELS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : Skin corrosion SKIN IRRITATION OF CHEMICALS The In vitro SkinEthic RHE Skin Corrosion as a Reference Test Method in the Acute Testing Strategy 2013 Society of Toxicology (SOT) Annual Meeting | L'Oréal, Research & Innovation
AUTHORS : Alepee N. Cotovio J Grandidier MH Meunier Jean-Roch Seyler N. Soler Francoise MODELS : EPISKIN APPLICATIONS : Skin corrosion SKIN IRRITATION OF CHEMICALS SYSTEMIC TOXICITY EpiSkin Acute Dermal Toxicity Testing Strategy - OECD TG 404 Acute Dermal Toxicity Testing Strategy Combining the Use of the EpiSkin Validated Test Methods 2012 SOT Society of Toxicology annual meeting | L'Oréal, Research & Innovation
AUTHORS : Auriault C. Cotovio J Cottrez F. Groux H. Lelièvre D Meunier Jean-Roch MODELS : EPISKIN APPLICATIONS : SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS IRR-IS® - EpiSkinTM based model for Irritation - Evaluation of IRR-IS®, an EpiSkinTM based model for Quantifying Chemical Irritation Potency 2012 SOT Society of Toxicology annual meeting | L’Oréal Research and Innovation, ImmunoSearch
AUTHORS : Alepee N. Cotovio J Duché Daniel Leclaire J Marrot L Ouedraogo G. Ovigne Jean-Marc Teissier M H MODELS : EPISKIN HCE / HUMAN CORNEAL EPITHELIUM RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : GENOTOXICITY OCULAR IRRITATION OF CHEMICAL Phototoxicity Skin corrosion SKIN IRRITATION OF CHEMICALS SKIN METABOLISM L’Oréal commitment in the develo pment, evaluation and validation of screening and testing approaches contributing to the 3Rs 2011 | L'Oréal
AUTHORS : Alepee N. Cotovio J de Brugerolle de Fraissinette A. Grandidier M H Meunier Jean-Roch Roquet Manon Seyler N. Soler Francoise Tornier C MODELS : EPISKIN RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : SKIN IRRITATION OF CHEMICALS An Evaluation of the EpiSkinTM and SkinEthicTM RHE test methods for predicting dermal toxicity using OECD TG404 2011 | L'Oreal
AUTHORS : Alepee N. Cotovio J Grandidier MH Lelièvre D Meunier Jean-Roch Tornier C MODELS : EPISKIN RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : SKIN IRRITATION OF CHEMICALS Evaluation of the in vitro EpiSkin and SkinEthic RHE Skin Irritation test methods for hazard identification of chemicals 2011 |