AUTHORS : Alves RC Beatriz M Ferreira M Helena Amaral M Oliveira PP Pereira C Pimentel FB Rodrigues F Sarmento B MODELS : EPISKIN HCE / HUMAN CORNEAL EPITHELIUM APPLICATIONS : SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS Are coffee silverskin extracts safe for topical use? An in vitro andin vivo approachF 2014 Elsevier | REQUIMTE, INEB, Inovapotek, IINFACTS, Department of Drug Sciences, Laboratory of Pharmaceutical Technology, Fourmag Lda
AUTHORS : Alepee N. Bessou S. Cotovio J De Smedt A De Wever B Faller C Jones P A Le Varlet Béatrice Marrec-Fairley M McNamee P Pfannenbecker U Tailhardat M Van Goethem F MODELS : HCE / HUMAN CORNEAL EPITHELIUM APPLICATIONS : OCULAR IRRITATION OF CHEMICAL Cosmetics Europe Multi-Laboratory Pre-Validation of the SkinEthic™ Reconstituted Human Corneal Epithelium Test Method for the Prediction of Eye Irritation. 2013 Toxicology in vitro | L'Oreal
AUTHORS : Alepee N. Bessou S. Boullay E. De Smedt A De Wever B Gregoire S. Jones P A Kunkel A. McNamee P Millet M. Pfannenbecker U Taalman R. Tailhardat M. Van Goethem F Wargniez W. MODELS : HCE / HUMAN CORNEAL EPITHELIUM APPLICATIONS : OCULAR IRRITATION OF CHEMICAL In vitro Eye Irritation RhT Test Methods for Dyes. COLIPA Program on Optimization and Validation of HPLC Bio-Analytical Assay to Expand Applicability Domain of in vitro Eye Irritation RhT Test Methods for Dyes. 2012 SOT Society of Toxicology annual meeting | L'Oréal Research & Innovation, Pierre Fabre, Janssen Research & Development, Henkel AG & Co. KGaA, Unilever, Beiersdorf, The Procter & Gamble Company, COLIPA, LVMH Recherche
AUTHORS : Beach D. Kazmi Perveen Orak Deborah Re Thomas Srinivasan V. MODELS : HCE / HUMAN CORNEAL EPITHELIUM APPLICATIONS : OCULAR IRRITATION OF CHEMICAL In vitro Ocular Testing 2012 SOT Society of Toxicology annual meeting | L'Oréal, Research & Innovation, USA
AUTHORS : Antignac E. Clouzeau J. Persaud R. Re Thomas Srinivasan V. MODELS : HCE / HUMAN CORNEAL EPITHELIUM APPLICATIONS : OCULAR IRRITATION OF CHEMICAL Safety Assessment of Botanicals 2012 SOT Society of Toxicology annual meeting | L'Oréal, Research & Innovation
AUTHORS : Antignac E. Clouzeau J. Persaud R. Re Thomas Srinivasan V. MODELS : EPISKIN HCE / HUMAN CORNEAL EPITHELIUM RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : GENOTOXICITY OCULAR IRRITATION OF CHEMICAL PHARMACOLOGY / TOXICOLOGY PHOTOPROTECTION Phototoxicity SKIN IRRITATION OF CHEMICALS SKIN IRRITATION OF COSMETICS SKIN SENSITIZATION SYSTEMIC TOXICITY Safety Assessment of Botanicals: A Decision Tree Approach for the Safety Assessment of Botanical Cosmetic Ingredients 2012 SOT Society of Toxicology annual meeting | L'Oréal, Research & Innovation
AUTHORS : Alepee N. Cotovio J Duché Daniel Leclaire J Marrot L Ouedraogo G. Ovigne Jean-Marc Teissier M H MODELS : EPISKIN HCE / HUMAN CORNEAL EPITHELIUM RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : GENOTOXICITY OCULAR IRRITATION OF CHEMICAL Phototoxicity Skin corrosion SKIN IRRITATION OF CHEMICALS SKIN METABOLISM L’Oréal commitment in the develo pment, evaluation and validation of screening and testing approaches contributing to the 3Rs 2011 | L'Oréal
AUTHORS : Alepee N. Blond S. Cotovio J Duché Daniel Eilstein Joan Grandidier MH Meunier Jean-Roch MODELS : HCE / HUMAN CORNEAL EPITHELIUM APPLICATIONS : OCULAR IRRITATION OF CHEMICAL In vitro Assessment of Eye Tolerance using the SkinEthic HCE Test Method Applied to Ingredients Used in Cosmetic 2011 | L'Oreal
AUTHORS : Alepee N. Amsellem Carole Bertino Beatrice Bremond Christelle Capallere Christophe Cotovio J de Brugerolle de Fraissinette A. Grandidier MH Leclaire J Lee AV Lelièvre D Loisel-Joubert Sophie Maloug Saber Meunier Jean-Roch Minondo Anne-Marie Ovigne Jean-Marc Tinois-Tessonneaud Estelle MODELS : HCE / HUMAN CORNEAL EPITHELIUM APPLICATIONS : Eye irritation OCULAR IRRITATION OF CHEMICAL In vitro assessment of eye irritancy using the Reconstructed Human Corneal Epithelial SkinEthic HCE model: application to 435 substances from consumer products industry. 2010 Toxicology In Vitro. 2010 Mar;24(2):523-37. | L'Oréal, Research & Innovation
AUTHORS : Jessen Bart A. Khoh-Reiter Su MODELS : HCE / HUMAN CORNEAL EPITHELIUM Evaluation of the cytotoxic effects of ophthalmic solutions containing benzalkonium chloride on corneal epithelium using an organotypic 3-D model 2009 | SkinEthic
AUTHORS : Alepee N. Amsellem Carole Bertino Beatrice Bremond Christelle Capallere Christophe Cotovio J de Brugerolle de Fraissinette A. Grandidier M H Leclaire J Lelièvre D Loisel-Joubert Sophie Maloug Saber Meunier Jean-Roch Minondo Anne-Marie Ovigne Jean-Marc Tinois-Tessonneaud Estelle Van Der Lee Aline MODELS : HCE / HUMAN CORNEAL EPITHELIUM In vitro assessment of eye irritancy using the Reconstructed Human Corneal Epithelial SkinEthic™ HCE model: Application to 435 substances from consumer products industry 2009 | SkinEthic
AUTHORS : Baudouin Christophe De Servi Barbara Le Varlet Béatrice Meloni M Pauly Aude MODELS : HCE / HUMAN CORNEAL EPITHELIUM Occludin gene expression as an early in vitro sign for mild eye irritation assessment 2009 Elsevier Toxicology in vitro | Vitroscreen
AUTHORS : Baudouin Christophe Brignole-Baudouin Francoise Meloni M Pauly Aude Warnet Jean-Michel MODELS : HCE / HUMAN CORNEAL EPITHELIUM APPLICATIONS : PHARMACOLOGY / TOXICOLOGY Multiple Endpoint Analysis of the 3D-Reconstituted Corneal Epithelium after Treatment with Benzalkonium Chloride: Early Detection of Toxic Damage 2009 lnvestigative Ophtalmology & Visual Science | Vitroscreen
AUTHORS : CORDONE LORENZO DE CARO VIVIANA GIANDALIA GIULIA GIANNOLA LIBERO I. SIRAGUSA MARIA G. MODELS : HCE / HUMAN CORNEAL EPITHELIUM Ocular Gelling Microspheres: In Vitro Precorneal Retention Time and Drug Permeation Through Reconstituted Corneal Epithelium 2008 | SkinEthic
AUTHORS : Hensen H. Kleber M Mehling A MODELS : HCE / HUMAN CORNEAL EPITHELIUM APPLICATIONS : OCULAR IRRITATION OF CHEMICAL Comparative studies on the ocular and dermal irritation potential of surfactants 2007 Food Chem Toxicol. 2007 May;45(5):747-58 | Cognis Deutschland GmbH and Co.KG, Henkelstr. 67, 40551 Duesseldorf, NRW, Germany. [email protected]; [email protected]
AUTHORS : Adriaens E. Alepee N. Cappadoro M Catoire S De Wever B Hansen E Straube F Van Goethem F Vanparys P Wolf A MODELS : HCE / HUMAN CORNEAL EPITHELIUM APPLICATIONS : OCULAR IRRITATION OF CHEMICAL Prevalidation of a new in vitro reconstituted human cornea model to assess the eye irritating potential of chemicals 2006 Toxicol In Vitro. 2006 Feb;20(1):1-17. Epub 2005 Jul 12. | Johnson & Johnson Pharmaceutical Research and Development, Turnhoutseweg 30, B-2340 Beerse, Belgium. [email protected]
AUTHORS : D'Cruz OJ Uckun FM. Waurzyniak B MODELS : HCE / HUMAN CORNEAL EPITHELIUM Mucosal toxicity studies of a gel formulation of native pokeweed antiviral protein. 2004 Toxicol Pathol. 2004 Mar-Apr;32(2):212-21. | Drug Discovery Program, Department of Reproductive Biology, Parker-Hughes Institute, 2657 Patton Road, St. Paul, Minnesota 55113, USA. [email protected]