AUTORES : Elsaesser C Fraissinette Ade B. Greiner B Kolopp M Mahl A Medina J Meingassner J Nussbaumer P Picarles V Roman D Vogel B Winiski A LAV694, a new antiproliferative agent showing improved skin tolerability vs. clinical standards for the treatment of actinic keratosis 2003 Biochem Pharmacol. 2003 Nov 15;66(10):1885-95. | Preclinical Safety Department, Novartis Pharma AG, WSH.2881.P03, CH-4002 Basel, Switzerland.
AUTORES : Chibout S D de Brugerolle de Fraissinette A Elsaesser C Grenet O Kolopp M Medina J Picarles V APLICAÇÕES : Phototoxicity Assessment of the phototoxic potential of compounds and finished topical products using a human reconstructed epidermis 2001 In Vitr Mol Toxicol 2001 Fall ;14 (3):157-68 | Preclinical Safety Department, Novartis Pharma AG, WSJ-386.1151, CH-4002 Basel, Switzerland.
AUTORES : Chibout SD de Brugerolle de Fraissinette A. Elsaesser C Grenet O Kolopp M Medina J Picarles V Assessment of the phototoxic potential of compounds and finished topical products using a human reconstructed epidermis 2001 In Vitr Mol Toxicol. 2001 Fall;14(3):157-68. | Preclinical Safety Department, Novartis Pharma AG, WSJ-386.1151, CH-4002 Basel, Switzerland.
AUTORES : Burtin P Chibout S D Cordier A de Brugerolle de Fraissinette Ebelin M E Kammermann R Kolopp M Medina J APLICAÇÕES : SKIN IRRITATION OF CHEMICALS Use of human skin equivalent Apligraf for in vitro assessment of cumulative skin irritation potential of topical products 2000 Toxicol Appl Pharmacol 2000 ;164 (1):38-45 | Preclinical Safety Department, Novartis Pharma AG, Basel, CH-4002, Switzerland. [email protected]
AUTORES : Burtin P Chibout S Cordier A. de Brugerolle de Fraissinette De Wever B Ebelin ME Ettlin RA Kolopp M Mayer FK Medina J Osborne S Picarles V Rosdy M Spake A MODELOS : RHE / RECONSTRUCTED HUMAN EPIDERMIS APLICAÇÕES : SKIN IRRITATION OF CHEMICALS Predictivity of an in vitro model for acute and chronic skin irritation (SkinEthic) applied to the testing of topical vehicles. 1999 Cell Biol Toxicol. 1999 Apr;15(2):121-35. | Novartis Pharma AG, Basel, Switzerland.